Topical and systemic anticholinergic for treating hyperhidrosis

Ada Regina Trindade de Almeida, Vanessa Rocha de Moura Moreira, Fernanda Ferrari


Topical and systemic anticholinergic drugs continue to be useful medications in the management of Hyperhidrosis and accordingly to the International Hyperhidrosis Society (IHHS) algorithm for treatment, they are the initial therapeutic option for all primary forms of excessive sweating. In this article, several topical and systemic agents will be reviewed and information about efficacy, safety and side effects will be discussed.